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Ivermectin for the treatment of resistant scabies
Aaron M Cook1, Frank Romanelli
1University of Texas Medical Branch, Galveston, TX 77555-0701, USA. amcook@utmb,edu
Objective:
To assess the clinical literature describing the use of ivermectin in cases of treatment-resistant scabies infestations.
Data Sources:
Clinical literature accessed through a MEDLINE search (1966-July 2001) and the Cochrane Database.
Data Synthesis:
A limited number of case reports and case series describes successful intervention with ivermectin use in patients who have failed prior therapy. Ivermectin may serve as a viable alternative therapy as the incidence of resistant scabitic infestations increases.
Conclusions:
Ivermectin appears to be a safe and effective alternative for patients with treatment-resistant scabies. Larger, controlled clinical trials are required before this therapy can be recommended in the general population or as primary therapy.