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Gabapentin for the treatment of tremor
Michele A Faulkner1, John M Bertoni, Thomas L Lenz
1School of Pharmacy and Allied Health Professions, Creighton University, Omaha, NE 68178-0401, USA. faulkner@creighton.edu
Objective:
To review the use of the antiepileptic drug gabapentin for the treatment of various types of tremor.
Data Sources:
A search of biomedical literature was completed through MEDLINE and EMBASE (1993-May 2002) to identify all clinical trials pertaining to the use of gabapentin for the treatment of tremor in humans.
Data Synthesis:
Outcome data from the few published studies have varied widely. Patient groups have been small, and conclusions have been based largely on subjective patient and investigator ratings.
Conclusions:
A trial of gabapentin is warranted in patients who fail therapy with traditional agents. Improvement should be measured by a patient's perceived functional ability.