Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[beta-Lactam antibiotics].

Mar Marín1, Francesc Gudiol

  • 1Servicio de Enfermedades Infecciosas. Hospital de Bellvitge. Universidad de Barcelona. Hospitalet de Llobregat. Barcelona. España.

Enfermedades Infecciosas Y Microbiologia Clinica
|January 29, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Endoscopic ultrasound-guided biliary rendezvous after failed cannulation, and comparison between benign vs malignant biliopancreatic disorders: outcomes at a single tertiary-care centre.

Annals of medicine·2024
Same author

The Etiology, Antibiotic Therapy and Outcomes of Bacteremic Skin and Soft-Tissue Infections in Onco-Hematological Patients.

Antibiotics (Basel, Switzerland)·2023
Same author

Leveraging a nationwide infection surveillance program to implement a colorectal surgical site infection reduction bundle: a pragmatic, prospective, and multicenter cohort study.

International journal of surgery (London, England)·2023
Same author

Spinal cord compression of neoplastic origin: surgical experience using a common clinical language.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·2022
Same author

COVID-19 in breast cancer patients: a subanalysis of the OnCovid registry.

Therapeutic advances in medical oncology·2021
Same author

Antibiotic consumption trends among acute care hospitals in Catalonia (2008-2016): impact of different adjustments on the results.

Expert review of anti-infective therapy·2020
Same journal

New COVID-19 vaccination recommendations in Spain: Optimizing for next seasons.

Enfermedades infecciosas y microbiologia clinica·2025
Same journal

[Description of 12 HIV-positive patients who have had the COVID-19 in our area].

Enfermedades infecciosas y microbiologia clinica·2024
Same journal

[SARS-CoV-2 infection as trigger multisystem inflammatory syndrome?]

Enfermedades infecciosas y microbiologia clinica·2024
Same journal

Impact of COVID-19 on Madrid hospital system.

Enfermedades infecciosas y microbiologia clinica·2024
Same journal

[COVID-19 and influenza A coinfection: a matter of principle].

Enfermedades infecciosas y microbiologia clinica·2024
Same journal

COVID and CARE®. Mobile application for monitoring SARS-CoV-2 positive patients after hospitalization.

Enfermedades infecciosas y microbiologia clinica·2024
See all related articles

Betalactams are essential antimicrobials inhibiting bacterial cell walls. Despite emerging resistance, they remain crucial for treating various infections, with specific types like penicillin and carbapenems retaining key roles.

Area of Science:

  • Pharmacology and Microbiology
  • Antimicrobial Agents
  • Bacterial Cell Wall Synthesis

Context:

  • Betalactams represent the largest and most utilized class of antimicrobial drugs.
  • They function by inhibiting the final stages of bacterial cell wall biosynthesis.
  • These agents exhibit slow bactericidal activity, low toxicity, and a wide therapeutic index.

Purpose:

  • To review the role and evolution of betalactam antibiotics in clinical practice.
  • To discuss the impact of increasing bacterial resistance on betalactam efficacy.
  • To highlight current applications of various betalactam classes and inhibitors.

Summary:

  • Betalactams are vital antimicrobials, inhibiting bacterial cell wall synthesis with favorable pharmacokinetic and safety profiles.

Related Experiment Videos

  • While resistance is a growing concern, specific betalactams like penicillin, cephalosporins, and carbapenems remain indispensable.
  • Betalactamase inhibitors are crucial for overcoming resistance and extending the utility of certain penicillin derivatives.

    • Impact:

    • Betalactams continue to be foundational in treating a broad spectrum of bacterial infections.
    • Understanding resistance mechanisms is critical for preserving the effectiveness of these essential drugs.
    • Strategic use of different betalactam classes and adjunct therapies ensures optimal patient outcomes.