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Updated: Sep 27, 2026

The Use of Magnetic Resonance Spectroscopy as a Tool for the Measurement of Bi-hemispheric Transcranial Electric Stimulation Effects on Primary Motor Cortex Metabolism
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The Use of Magnetic Resonance Spectroscopy as a Tool for the Measurement of Bi-hemispheric Transcranial Electric Stimulation Effects on Primary Motor Cortex Metabolism

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Effects of electroconvulsive therapy on regional cerebral blood flow measured by 99mtechnetium HMPAO SPECT

Mboyo Di Tamba Vangu1, Jan Daniel Esser, Ivan Harry Boyd

  • 1Division of Nuclear Medicine, Johannesburg Hospital, Private Bag x39, Johannesburg 2000, South Africa. 084mboy@chiron.wits.ac.za

Progress in Neuro-Psychopharmacology & Biological Psychiatry
|January 29, 2003
PubMed

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Electroconvulsive Therapy01:30

Electroconvulsive Therapy

Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early years,...