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Related Experiment Videos

Radionuclide imaging in the post-genomic era.

Uwe Haberkorn1, Annette Altmann

  • 1Department of Nuclear Medicine, University of Heidelberg, Germany. Uwe_Haberkorn@med.uni-heidelberg.de

Journal of Cellular Biochemistry. Supplement
|January 29, 2003
PubMed
Summary

High-throughput genomic tools enable the study of gene function and biological pathways. These methods advance cell research, protein network analysis, and the development of novel diagnostic and therapeutic biomolecules.

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Area of Science:

  • Genomics
  • Proteomics
  • Biochemistry

Background:

  • Human genome sequencing completion necessitates advanced gene function assessment tools.
  • High-throughput methods evaluate global gene expression changes for pathway investigation.
  • Proteomics offers proteome-wide protein descriptions and network analysis.

Purpose of the Study:

  • To explore the application of genome program tools for gene function assessment.
  • To investigate the integration of physiological, biochemical, and pharmacological approaches with new technologies.
  • To highlight the role of nuclear medicine and pharmacogenomics in disease research and drug development.

Main Methods:

  • Utilizing high-throughput methods for simultaneous gene expression analysis.
  • Employing proteome-wide scale descriptions for cell research and protein network analysis.

Related Experiment Videos

  • Applying in vivo imaging techniques like SPECT and PET for evaluating genetically manipulated models and biomolecules.

    • Main Results:

    • Determination of three-dimensional protein structures and protein networks.
    • Design of new hypotheses and experiments in physiology, biochemistry, and pharmacology.
    • Application of nuclear medicine procedures with tracers or reporter genes for gene function determination.

    Conclusions:

    • Advanced genomic and proteomic tools revolutionize cell research and hypothesis generation.
    • In vivo imaging and nuclear medicine are crucial for evaluating genetic modifications and biomolecules.
    • Pharmacogenomics and bioengineering pave the way for novel diagnostic and therapeutic strategies.