Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Juvenile astrocytomas with subarachnoid spread.

J E McLaughlin

    The Journal of Pathology
    |February 1, 1976
    PubMed
    Summary

    Extracerebellar astrocytomas can spread to the subarachnoid space and surrounding structures. Features like nuclear abnormalities and oligodendrocytomatous areas suggest a poorer prognosis for these juvenile astrocytomas.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Qualitative evaluation of postdoctoral trainee and faculty advisor experiences within a research-intensive school of pharmacy.

    BMC medical education·2022
    Same author

    Business models and provider satisfaction in in vitro fertilization centers in the USA.

    Journal of assisted reproduction and genetics·2018
    Same author

    Henry Urich 15 August 1916-9 November 2015.

    Neuropathology and applied neurobiology·2016
    Same author

    Ortner syndrome and haemophilia.

    Haemophilia : the official journal of the World Federation of Hemophilia·2005
    Same author

    Hodgkin Lymphoma in a patient with mycosis fungoides: molecular evidence for separate cellular origins.

    The British journal of dermatology·2003
    Same author

    Isolated B-cell lymphoma of the pituitary region: a rare clinical entity.

    Hospital medicine (London, England : 1998)·2002

    Area of Science:

    • Neuro-oncology
    • Surgical Pathology
    • Pediatric Neurosurgery

    Background:

    • Extracerebellar astrocytomas are rare brain tumors.
    • Subarachnoid spread and invasion of surrounding structures are aggressive features.
    • Understanding prognostic indicators is crucial for patient management.

    Purpose of the Study:

    • To present surgical and necropsy findings in five cases of extracerebellar astrocytoma.
    • To identify histological features associated with prognosis.
    • To correlate tumor characteristics with patient outcomes.

    Main Methods:

    • Review of surgical and necropsy findings in five patients.
    • Histological examination of tumor tissue.
    • Correlation of histological features with clinical data and outcomes.

    Main Results:

    • Five cases of extracerebellar astrocytoma with subarachnoid spread and invasion were analyzed.
    • Patients aged 6-23 years, with fatal outcomes within 20 months.
    • Histology showed piloid astrocytes with nuclear abnormalities and, in some cases, oligodendrocytomatous foci.

    Conclusions:

    • Nuclear pleomorphism and oligodendrocytomatous areas in juvenile astrocytomas indicate a poor prognosis.
    • These features may be associated with partly anaplastic tumors.
    • Early identification of these indicators is vital for treatment planning.

    Related Experiment Videos