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[The research of evaluation the compatibility of biotic material in cell-culturing method]
1Department of Thoracocardiac Surgery, First University Hospital, West China University of Medical Science, Chengdu 610041.
Abstract:
It is quick convienent good-repeating and cheap that examining the biotic material's compatibility through cell-culturing method, and it is more and more important in evaluating the compatibility of biotic material. The new material appearing continously complicating of the part and aim material be planted in the intensity of material's toxic effect the reaction's complication of material and biotic body, all of these decide the variety of experiment method and cells in cell toxicity experiment. It is very important that choices the right experiment method and cells according to the material's character the part and aim the material be planted in. The evaluation of biotic material's compatibility stressed on the changing of cell's form and quantity before. In recent years, more and more reports appear about material influences the growth. Adhesion proliferation and metabolizing of cell, and presents the point that the evaluation standard of biotic material's compatibility should be set according to the active cell's quantity and their growth. Combining many subject's technological development, such as immunology, chemistry, radiation and shadowgraphy, thoroughly inquires the changing relation of cell's structure and function, furtherly clarifes the material's effect on cell. It is the developing direction in the future that evaluates the biotic material's compatibility in cell-culturing method.