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Human immunodeficiency virus type 1 RNA polymerase chain reaction reasonably excludes infection in exposed infants
Jorge Luján-Zilbermann1, Wally Bitar, Katherine Knapp
1Department of Inectious Diseases, St Jude Children's Research Hospital, Department of Pediatrics, University of Tennessee Health Science Center, Memphis, USA.
The Pediatric Infectious Disease Journal
|January 30, 2003
Abstract:
A nucleic acid sequence-based amplification (NASBA) assay that detects HIV RNA may be helpful in excluding perinatal HIV infection. We reviewed the records of 190 infants born to HIV-infected mothers. The sensitivity and specificity of the NASBA assay were 100% when measured at two time periods in the first 9 months of life. The HIV RNA NASBA assay should be considered a valid diagnostic test in this population.