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Nasal septal perforation caused by invasive fungal sinusitis

Wai-Tin Kuo1, Ta-Jen Lee, Ying-Lin Chen

  • 1Department of Otolaryngology, Chang Gung Memorial Hospital, Taipei, Taiwan, ROC.

Insights

Nasal septal perforation is a rare complication of invasive fungal sinusitis. This case highlights a potential link between invasive aspergillosis sinusitis and nasal septal perforation, a condition previously reported only once.

Area of Science:

  • Otorhinolaryngology
  • Mycology
  • Surgical Pathology

Background:

  • Nasal septal perforation poses significant challenges in otorhinolaryngology.
  • Previous septal surgery is the most frequent cause of nasal septal perforation.
  • Invasive fungal sinusitis is a serious condition requiring prompt diagnosis and treatment.

Observation:

  • A 57-year-old woman with recurrent chronic sinusitis underwent endoscopic sinus surgery.
  • A left nasal mass was excised during the procedure.
  • Invasive aspergillosis sinusitis was diagnosed both grossly and histopathologically.
  • A nasal septal perforation was incidentally noted during the operation.

Findings:

  • The patient presented with invasive aspergillosis sinusitis.
  • A nasal septal perforation was identified concurrently with the fungal sinusitis.
  • This represents the second reported case of nasal septal perforation associated with invasive fungal sinusitis.

Implications:

  • Invasive fungal sinusitis may be an underrecognized cause of nasal septal perforation.
  • Further research is needed to understand the mechanism and incidence of this rare complication.
  • This finding may influence diagnostic and management strategies for invasive fungal sinusitis.

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