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Improving the Success Rate of Protein Crystallization by Random Microseed Matrix Screening
Published on: August 31, 2013
The advantages of using a modified microbatch method for rapid screening of protein crystallization conditions
Allan D'Arcy1, Aengus Mac Sweeney, Martine Stihle
1Morphochem AG Basel, Switzerland. allan.darcy@morphochem.ch
Acta Crystallographica. Section D, Biological Crystallography
|January 30, 2003
Abstract:
In this study, characterization and optimization of a modified microbatch crystallization technique has been attempted in order to provide a rapid screening method. Using this method for screening has certain advantages over standard vapour-diffusion methods: no sealing of drops is required, no reservoir solutions are needed and the experiments can easily be performed over a range of temperatures.

