Toll signaling: the TIReless quest for specificity

Toll-like receptors in innate immunity and inflammation: from fundamental biology to clinic insights.

Immunity & inflammation·2026

From Drosophila to mammals: The evolutionarily conserved homeodomain protein Engrailed affects the antitumor innate immune response.

Proceedings of the National Academy of Sciences of the United States of America·2026

FADD is recruited to activated STING oligomers to initiate caspase-mediated NF-κB activation in Drosophila melanogaster.

The EMBO journal·2026

α2-macroglobulin function of thioester-containing proteins guards Drosophila from a bacterial protease via two immune-induced peptides.

Proceedings of the National Academy of Sciences of the United States of America·2026

Regulation of detoxifying enzymes expression and restriction of picorna-like virus infection by natural polysaccharide extracts in Drosophila cells.

Virology·2025

Argonaute 2 targets viral transcripts but not genomes of RNA viruses during antiviral RNA interference in Drosophila.

PLoS pathogens·2025

Tissue-resident immune cells drive genetic risk in autoimmune and lung diseases.

Nature immunology·2026

BCAT2 links branched-chain amino acids metabolism to interferon signaling to sustain macrophage inflammation.

Nature immunology·2026

Human lungs maintain tissue-resident memory T cells against a broad spectrum of pathogens.

Nature immunology·2026

Dysbiosis-induced expansion of AXL-positive inflammatory type 3 dendritic cells triggers preclinical autoimmunity.

Nature immunology·2026

Endothelial cell-intrinsic NOD2 signaling regulates the intestinal immune response through the generation of effector and memory T cells.

Nature immunology·2026

Rediscovering eosinophil identity through tissue adaptation.

Nature immunology·2026

Enhancing Externalization of Frontal Virtual Sound Sources in Binaural Synthesis via Level and Reflection Adjustment of Non-individualized BRIRs.

Trends in hearing·2026

Sequential Bilateral Cochlear Implantation via the Transmastoid Labyrinthotomy Approach Using Custom-Made Electrodes in a Pediatric Patient With Common Cavity Deformities: A Case Report.

Case reports in otolaryngology·2026

Lifetime imaging reveals long-distance non-neural bioelectric patterns on timescales from seconds to hours.

Developmental biology·2026

A biodegradable piezoelectric vertebral implant for programmable electro-neuromodulation in spinal cord injury.

Science advances·2026

Transcranial focused ultrasound enhances the discriminative power of targeted voluntary motor signals in humans.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society·2026

EpiCure (Epithelial Curation): a versatile and handy tool for curation of epithelial segmentation.

Development (Cambridge, England)·2026

Related Experiment Videos

Toll signaling: the TIReless quest for specificity

Related Concept Videos

Toll-like receptors in innate immunity and inflammation: from fundamental biology to clinic insights.

From Drosophila to mammals: The evolutionarily conserved homeodomain protein Engrailed affects the antitumor innate immune response.

FADD is recruited to activated STING oligomers to initiate caspase-mediated NF-κB activation in Drosophila melanogaster.

α2-macroglobulin function of thioester-containing proteins guards Drosophila from a bacterial protease via two immune-induced peptides.

Regulation of detoxifying enzymes expression and restriction of picorna-like virus infection by natural polysaccharide extracts in Drosophila cells.

Argonaute 2 targets viral transcripts but not genomes of RNA viruses during antiviral RNA interference in Drosophila.

Tissue-resident immune cells drive genetic risk in autoimmune and lung diseases.

BCAT2 links branched-chain amino acids metabolism to interferon signaling to sustain macrophage inflammation.

Human lungs maintain tissue-resident memory T cells against a broad spectrum of pathogens.

Dysbiosis-induced expansion of AXL-positive inflammatory type 3 dendritic cells triggers preclinical autoimmunity.

Endothelial cell-intrinsic NOD2 signaling regulates the intestinal immune response through the generation of effector and memory T cells.

Rediscovering eosinophil identity through tissue adaptation.

Enhancing Externalization of Frontal Virtual Sound Sources in Binaural Synthesis via Level and Reflection Adjustment of Non-individualized BRIRs.

Sequential Bilateral Cochlear Implantation via the Transmastoid Labyrinthotomy Approach Using Custom-Made Electrodes in a Pediatric Patient With Common Cavity Deformities: A Case Report.

Lifetime imaging reveals long-distance non-neural bioelectric patterns on timescales from seconds to hours.

A biodegradable piezoelectric vertebral implant for programmable electro-neuromodulation in spinal cord injury.

Transcranial focused ultrasound enhances the discriminative power of targeted voluntary motor signals in humans.

EpiCure (Epithelial Curation): a versatile and handy tool for curation of epithelial segmentation.

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Toll signaling: the TIReless quest for specificity

Related Concept Videos

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