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Updated: Sep 27, 2026

Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
Published on: March 27, 2018
[Surgery of heart insufficiency]
1Service de chirurgie cardiaque, hôpital Foch, BP 36, 40, rue Worth, 92151 Suresnes, France. g.dreyfus@hopital-foch.org
Insights
Surgical options like coronary bypass, Dor procedure, and mitral plasty offer alternatives to heart transplantation for heart failure. These procedures show promising results in improving patient function and survival rates.
Area of Science:
- Cardiovascular Surgery
- Heart Failure Management
- Surgical Techniques
Context:
- Heart transplantation is a primary treatment for heart failure, but surgical alternatives are crucial.
- Ischemic heart disease and enlarged heart disease present distinct surgical challenges.
- Patient selection criteria are vital for successful surgical interventions.
Purpose:
- To review and assess surgical approaches for heart failure beyond transplantation.
- To evaluate the efficacy and indications for coronary bypass, Dor procedure, and mitral plasty.
- To compare outcomes and limitations of various surgical techniques for heart failure.
Summary:
- Coronary bypass requires adequate myocardial reserve and absence of severe pulmonary hypertension.
- The Dor procedure reshapes the left ventricle, improving function in dyskinetic or akinetic cases.
- Mitral plasty techniques, including annuloplasty and specific procedures like Bolling's, address mitral failure.
- The Batista procedure reduces left ventricular size in severe cases, often combined with mitral plasty.
Impact:
- Surgical interventions demonstrate encouraging improvements in functional class and left ventricular function.
- These techniques provide viable alternatives to heart transplantation for select patients.
- Further research is needed to compare surgical outcomes with medical management and to refine advanced techniques.
Abstract:
Apart from heart transplantation for heart failure, the problem arises of which surgical approach should be adopted to treat this disorder. Ischemic heart disease can be surgically managed in three ways: via bypass, the Dor procedure, or by isolated or associated mitral plasty; however, cases of enlarged heart disease can only be surgically treated in two ways: i.e., by mitral plasty, or by the Batista procedure. In cases of ischemic heart disease, the following conditions must be present for coronary bypass: the patients should have an adequate contractile myocardial reserve, that is to say the left ventricle should not be greatly enlarged (< 80 mm in telediastole) or a cardiac output reserve, and there should not be any sign of over-high pulmonary hypertension (an index of > 1.6 or a pulmonary pressure of < 45); an assessment of myocardial viability should then be carried out, mainly based on a thallium fixation at rest and on echographically determined doubtamine-associated stress. In the present study, the mortality rate in a series of 260 patients was 6.3% for subjects aged under 70 years old, with an actuarial survival rate of 82% at one year post-surgery, and of 70% at five years. The Dor procedure can be used in the treatment of dyskinesia, which is now practically non-existent, but also in cases of acute akinesia with resulting left ventricular dysfunction. The aim of this technique is to alter the form of a cavity that has become ovoid to an elliptical form via the insertion of a circular endoventricular patch. The results reported for this technique show an improvement in functional class and ejection fraction. Finally, the technique for repairing mitral failure is more complicated than the two previous methods, as it requires a dynamic assessment of mitral failure, which is best carried out by an evaluation of echographically determined stress. Any mitral failure of ischemic origin of > grade 2 can be corrected during bypass surgery by ring insertion, thereby effecting a simple annuloplasty. On the other hand, the assessment of cases of enlarged heart disease is more complicated, and it is more difficult to carry out palliative surgery. The mitral plasty procedure proposed by Bolling is the technique of choice for patients with severe mitral failure, in general when the ventricle is not too enlarged. However, surgery involving the reduction in size of the left ventricle (the Batista procedure) always includes mitral plasty, and may be performed in patients with a very enlarged ventricle (> 70 mm), in general with moderate mitral failure. These two techniques have been critically assessed both as regards results and when they should be adopted, and their limitations have also been discussed. In conclusion, there are valid surgical alternatives to heart transplantation in cases of heart failure that does not respond to medical treatment, and they should probably be seriously considered before any decision is made to perform heart transplantation. These results appear encouraging, particularly in terms of functional class and left ventricular function, but there are conflicting results for hemodynamic improvement. As regards survival, it is not yet possible to propose prospective randomized trials to compare medical treatment with these surgical techniques. However, further development of these techniques is bound to occur, and an ever-widening gap will exist between the limited number of cases requiring transplantation and the more complex surgical approaches adopted in future, such as permanent circulatory backup or xenografts.
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