Synthesis and central nervous system depressant activity of some bicyclic amides

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Halogenated mazindol analogs as potential inhibitors of the cocaine binding site at the dopamine transporter.

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Antitumor activity of 5-aryl-2,3-dihydroimidazo[2,1-a]isoquinolines.

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In situ preparation of chiral-induced covalent organic framework stationary phase for enantioseparation of drugs.

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Synthesis and central nervous system depressant activity of some bicyclic amides

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High affinity recognition of serotonin transporter antagonists defined by species-scanning mutagenesis. An aromatic residue in transmembrane domain I dictates species-selective recognition of citalopram and mazindol.

Halogenated mazindol analogs as potential inhibitors of the cocaine binding site at the dopamine transporter.

Antitumor activity of the R- and S-enantiomers of RS-2-[[hydroxy[[2-[ (octadecyloxy)methyl]tetrahydrofuran-2-yl]methoxy]-phosphinyl]oxy]-N, N,N,-trimethylethylaminium hydroxide inner salt.

Preclinical pharmacology and possible mechanism of action of the novel antitumor agent 5-(4'-piperidinomethylphenyl)-2,3-dihydroimidazo [2,1-a]isoquinoline.

Antitumor activity of 5-aryl-2,3-dihydroimidazo[2,1-a]isoquinolines.

Antitumor activity of a piperidine phospholipid.

Structural and Mechanistic Studies of ADEPs Yield Potent Antibacterials and a Drug Formulation Strategy for Tuberculosis.

A 177Lu-Labeled Circular Bivalent Aptamer for PTK7-Targeting Radionuclide Therapy in Ovarian Cancer and Orthotopic Hepatoblastoma.

From Fragment Hit to Clinical Candidate: Discovery of Dual H1R/H4R Ligands with Superior Efficacy in Allergic Conjunctivitis.

Potent Anticancer Tethered Organorhodium(III) Complexes Target the Mitochondria.

Discovery of a Covalent NLRP3 LRR-Domain Probe: Reversing Renal Fibrosis via Immunometabolic Reprogramming in Organoid and Murine Models.

Lead Optimization of Multimutant KRAS Switch-II Pocket Macrocyclic Inhibitors via Isosteric Replacement to Improve ADME and Oral Exposure.

Protective Effect of Methoxsalen on Spinal Cord Injury in the Rat Model via Regulation of the PI3K/Akt Pathway.

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Corrigendum to "Computational screening of Sophora flavescens phytochemicals as potential aromatase inhibitors: Molecular docking, ADMET, Network pharmacology, Molecular dynamics simulation, and DFT studies" [Pharmaceutic. Sci. Adv. 4 (2026) 100108].

In situ preparation of chiral-induced covalent organic framework stationary phase for enantioseparation of drugs.

Small molecules dually targeting SARS-CoV-2 and host G-quadruplexes: binding mechanism explored by integrated experiments and computations.

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Synthesis and central nervous system depressant activity of some bicyclic amides

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