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Updated: Sep 27, 2026

Anti-virulent Disruption of Pathogenic Biofilms using Engineered Quorum-quenching Lactonases
Published on: January 1, 2016
[Production of D-pantolactone hydrolase by Fusarium moniliforme SW-902]
Yixin Tang1, Zhihao Sun, Lei Hua
1School of Biotechnology, Southern Yangtze University, Key Laboratory of Industry Biotechnology, Ministry of Education, Wuxi 214036, China.
Abstract:
Fusarium moniliforme SW-902, a high-yielding strain for producing D-pantolactone hydrolase was screened. The conditions for enzyme formation of the strain were studied. The suitable carbon source of the medium was glycerol and the suitable nitrogen source was peptone. The optimum temperature and initial pH for enzyme formation were 26 degrees C and pH8.0 respectively. When the organism was cultured in the 60 L-fermentor under the optimum conditions for 45 h, about 7.18 g dry cells/L and 0.92 IU/g dry cells weight were obtained.
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