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[Mediastinal tumors in children].
Krystyna Sawicz-Birkowska1, Jerzy Czernik, Rafał Chrzan
1Katedra i Klinika Chirurgii Pediatrycznej AM we Wrocławiu.
Polski Merkuriusz Lekarski : Organ Polskiego Towarzystwa Lekarskiego
|February 1, 2003
Summary
Mediastinal tumors in children are rare, with neurogenic tumors being the most common. Combined treatments improved outcomes for neurogenic cases, showing no significant changes in tumor prevalence over 30 years.
Area of Science:
- Pediatric Oncology
- Thoracic Surgery
- Diagnostic Imaging
Context:
- Mediastinal tumors are uncommon in pediatric populations.
- A 30-year retrospective study analyzed 125 pediatric cases.
- Tumor locations included anterior, medial, and posterior mediastinum.
Purpose:
- To evaluate clinical features, diagnostic methods, and surgical management of pediatric mediastinal tumors.
- To assess treatment outcomes, particularly for neurogenic tumors.
- To compare tumor prevalence over two distinct 30-year periods.
Summary:
- Neurogenic tumors (35%) were most frequent, followed by lymphatic origin tumors.
- Solid tumors constituted 78% of cases, with 68% occurring in children under 5.
- Complete excision was achieved in 66% of patients; open biopsy in 26%.
- Combined therapy (radiotherapy, chemotherapy, surgery) yielded a 71% 3-year complete remission rate for neurogenic tumors.
Impact:
- Provides insights into the epidemiology and management of pediatric mediastinal tumors.
- Highlights the efficacy of multimodal treatment for neurogenic mediastinal tumors.
- Establishes a baseline for future research on pediatric mediastinal neoplasms.