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Related Experiment Videos

Axillary hyperhidrosis: eccrine or apocrine?

A Lonsdale-Eccles1, N Leonard, C Lawrence

  • 1Department of Dermatology, James Cook University Hospital, Middlesbrough, UK.

Clinical and Experimental Dermatology
|February 1, 2003
PubMed
Summary
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This review examines axillary hyperhidrosis, exploring normal sweat gland function and the roles of eccrine, apocrine, and apo-eccrine glands in excessive underarm sweating.

Area of Science:

  • Dermatology
  • Physiology

Background:

  • Axillary hyperhidrosis is a common condition characterized by excessive underarm sweating.
  • Understanding sweat gland physiology is crucial for managing this condition.

Purpose of the Study:

  • To review the existing literature on axillary hyperhidrosis.
  • To discuss the normal function of sweat glands.
  • To explore the specific contributions of eccrine, apocrine, and apo-eccrine glands to excessive axillary sweating.

Main Methods:

  • Literature review of scientific articles and studies.
  • Analysis of research on sweat gland anatomy and function.
  • Pathophysiological correlation of gland activity with hyperhidrosis.

Main Results:

Related Experiment Videos

  • Eccrine glands are the primary producers of sweat for thermoregulation.
  • Apocrine glands contribute to odor and may play a role in hyperhidrosis.
  • Apo-eccrine glands, a hybrid type, are abundant in the axilla and likely involved in excessive sweating.

Conclusions:

  • Excessive axillary sweating involves complex interactions between eccrine, apocrine, and apo-eccrine glands.
  • Further research is needed to fully elucidate the pathophysiology of axillary hyperhidrosis.