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Atypical ductal hyperplasia presenting as pseudomicrocalcifications.

Henry C H Tsai¹, Helena Chang, Sanford H Barsky

¹Department of Pathology, UCLA School of Medicine, Los Angeles, California 90024, USA.

The Breast Journal

|February 1, 2003

Summary

Pseudomicrocalcifications, mimicking true microcalcifications on mammography, can arise from atypical ductal hyperplasia. Surgical excision confirmed these radiodensities were cellular proliferations, not true calcifications.

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Area of Science:

Radiology
Pathology
Breast Imaging

Background:

Mammography is a key tool for detecting breast abnormalities, including microcalcifications.
Microcalcifications can indicate various conditions, ranging from benign to malignant.

Observation:

A 53-year-old female presented with suspicious microcalcifications on mammography.
These "suspicious" findings prompted surgical excision for definitive diagnosis.

Findings:

Histopathological examination revealed pseudomicrocalcifications, not true calcifications.
The pseudomicrocalcifications were caused by dense intraductal cellular proliferations of atypical ductal hyperplasia.
The cellular density mimicked radiodensities typically associated with calcifications.

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Implications:

Highlights the importance of histopathological correlation for ambiguous mammographic findings.
Atypical ductal hyperplasia can present as radiodense lesions, requiring careful evaluation.
Understanding pseudomicrocalcifications improves diagnostic accuracy in breast imaging.