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Mixed tumor of deep soft tissue
Toshisada Adachi1, Yoshinao Oda, Akio Sakamoto
1Department of Anatomic Pathology, Pathological Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Pathology International
|February 1, 2003
Summary
This case report details a rare recurrent soft tissue mixed tumor that invaded bone. Surgical resection was successful, highlighting the importance of thorough evaluation for aggressive behavior in these rare soft tissue neoplasms.
Area of Science:
- Oncology
- Surgical Pathology
- Soft Tissue Neoplasms
Background:
- Mixed tumors are common in salivary glands and skin, but rare in soft tissues.
- Most soft tissue mixed tumors are presumed benign, with a small subset exhibiting aggressive behavior.
Observation:
- A patient presented with a recurrent mixed tumor in the deep subfascial soft tissue of the right lower leg.
- The primary tumor was adjacent to the fibula; local recurrence was noted one year post-initial resection.
- The recurrent tumor demonstrated infiltrative growth and invaded the adjacent fibula.
Findings:
- Histological examination of the recurrent tumor revealed extensive chondroid areas invading osseous tissue.
- Wide resection of the recurrent tumor was performed.
- The patient remained disease-free one year after the second surgery.
Implications:
- This case underscores the potential for aggressive behavior and bone invasion in soft tissue mixed tumors.
- Early and accurate diagnosis is crucial for effective management of these rare entities.
- Further research into the behavior of soft tissue mixed tumors is warranted.