Related Experiment Videos
The significance of adrenal metastases from lung carcinoma
I Kocijancic1, K Vidmar, M Zwitter
1Department of Radiology, Institute of Oncology, Zaloska 2, SI-1105 Ljubljana, Slovenia. ikocijancic@onko-i.si
Aim:
The aim of our study was to correlate spread of the lung cancer into the adrenal glands with the progression of the primary disease.
Methods:
We diagnosed and confirmed adrenal metastases in 50 patients with non-small cell lung cancer (NSCLC). We correlated the site of the primary lung carcinoma with the site of the adrenal metastasis, and the adrenal metastasis pattern, ipsi-, contra-, and bilateral adrenal metastases, with the operability and number of other sites of metastatic disease.
Results:
Adrenal metastases were ipsilateral in 20 patients, contralateral in 15 patients and bilateral in 15 patients. An inverse incidence of contra- and bilateral metastasis was observed in 37% of operated patients, and in 71% of patients with inoperable carcinoma. The difference between both groups was statistically significant (P=0.034).
Conclusions:
We suggest that an isolated ipsilateral adrenal metastasis in a patient with resectable primary NSCLC could be considered (and treated) as a localized disease rather than a symptom of systemic spread.
