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Human papillomavirus, it's genes...and cancer vaccines
1Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Caritas St. Elizabeth's Medical Center and Tufts-New England Medical Center, Tufts University School of Medicine, Boston, MA 02135, USA. michael_stellar@cchcs.org
Cancer Cell
|February 1, 2003
Abstract:
Genital human papillomavirus (HPV) infection is causally linked to the development of cervical cancer, a leading cause of cancer-related mortality in women worldwide. Recent studies demonstrate the effectiveness of virus-like particle-based vaccines to induce neutralizing antibodies against HPV and prevent cervical intraepithelial neoplasia.