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[Renal function during passive orthostasis (author's transl)].

P von Dittrich, W Stühlinger, G Flora

    Klinische Wochenschrift
    |February 15, 1976
    PubMed
    Summary
    This summary is machine-generated.

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    Mountaineers experienced a sharp decline in glomerular filtration rate (GFR) and renal plasma flow (RPF) during rope suspension. This suggests a risk of acute kidney injury in climbers after prolonged suspension.

    Area of Science:

    • Physiology
    • Nephrology
    • Altitude Medicine

    Context:

    • Assesses kidney function in mountaineers under suspension stress.
    • Investigates physiological responses to extreme conditions.

    Purpose:

    • To measure glomerular filtration rate (GFR) and renal plasma flow (RPF) in mountaineers before and during suspension.
    • To determine the impact of suspension on renal function.

    Summary:

    • Glomerular filtration rate (GFR) decreased from 123.0 +/- 14.9 ml/min to 25.3 +/- 3.9 ml/min.
    • Renal plasma flow (RPF) decreased from 791.0 +/- 101.0 ml/min to 129.0 +/- 20.4 ml/min within 24 minutes.
    • Measurements were taken using inulin and PAH clearance via a two-step permanent infusion technique.

    Impact:

    Related Experiment Videos

    • Findings indicate a high risk of acute renal failure in mountaineers after free suspension.
    • Highlights the potential for significant kidney impairment in climbers post-suspension.