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Related Experiment Videos

[Two patients with pseudogout manifested by severe neck pain].

Takuhiro Yoshida1, Yoshiki Sekijima, Ken-ichi Hoshi

  • 1Third Department of Medicine, Shinshu University School of Medicine, Shinshu University Hospital.

Rinsho Shinkeigaku = Clinical Neurology
|February 4, 2003
PubMed
Summary

Pseudogout, or calcium pyrophosphate dihydrate deposition, can cause severe neck pain in elderly patients. Cervical spine CT is crucial for diagnosing this rare condition.

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Area of Science:

  • Rheumatology and Orthopedics
  • Medical Imaging and Diagnostics

Background:

  • Pseudogout (calcium pyrophosphate dihydrate deposition disease) is a crystal-induced arthropathy.
  • Cervical spine involvement is rare, typically affecting older individuals.
  • Posterior neck pain can be an unusual presentation of cervical pseudogout.

Observation:

  • Two elderly patients presented with severe posterior neck pain, fever, and elevated inflammatory markers (ESR, CRP).
  • Standard cervical spine imaging (X-ray, MRI) and cerebrospinal fluid analysis were inconclusive.
  • Cervical CT revealed characteristic calcifications in the ligamenta flava (C3-C7) in both patients.

Findings:

  • Diagnosis of cervical pseudogout was confirmed via CT findings of ligamenta flava calcifications.
  • Patients responded well to non-steroidal anti-inflammatory drugs (NSAIDs), indicating an inflammatory component.

Related Experiment Videos

  • This presentation highlights a rare but significant cause of neck pain in the elderly.

    • Implications:

    • Cervical spine CT is essential for diagnosing pseudogout when neck pain is severe and unexplained.
    • Clinicians should consider cervical pseudogout in the differential diagnosis of elderly patients with posterior neck pain.
    • Early diagnosis and treatment with NSAIDs can lead to rapid symptom resolution.