[Studies on the genotoxic effects of acrylonitrile]

The effect of acrylonitrile (AN) on the reproduction was investigated in 341 male and 365 female exposed workers, 384 male and 438 female unexposed controls by questionnaires on the process of childbearing and the outcome of child birth. The results showed that AN caused menstrual disorder and dysgenesis in exposed female workers and the wife of exposed male workers. It is concluded that AN is harmful to the reproduction of exposed male and female workers.