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Related Experiment Videos

Appositional bone formation in marginal defects at implants.

Daniele Botticelli1, Tord Berglundh, Daniel Buser

  • 1Department of Periodontology, Faculty of Odontology, Sahlgrenska Academy at Göteborg University, Göteborg, Sweden. daniele.botticelli@odontologi.gu.se

Clinical Oral Implants Research
|February 4, 2003
PubMed
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Marginal defects around implants heal through new bone growth from surrounding bone walls. This process leads to significant osseointegration, even in wide defects, enhancing implant stability.

Area of Science:

  • Biomaterials Science
  • Dental Implantology
  • Bone Regeneration

Background:

  • Previous studies indicated that wide marginal defects around implants can achieve substantial osseointegration.
  • Understanding de novo bone formation in such defects is crucial for improving dental implant success rates.

Purpose of the Study:

  • To evaluate the degree and quality of new bone formation and osseointegration in marginal defects adjacent to submerged titanium implants.
  • To investigate the healing process in surgically created defects around dental implants.

Main Methods:

  • Four Labrador dogs underwent mandibular premolar and molar extractions.
  • Custom-made sandblasted, large grit, acid-etched (SLA) surface implants were placed in control sites; test sites involved widening the canal with a step drill and using a barrier membrane.

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  • Biopsies were collected two months post-implantation for histological analysis.

    • Main Results:

    • In control sites, bone remodeling allowed newly formed bone to contact the SLA surface.
    • In test sites, surgically created defects gradually filled with de novo bone originating from the defect walls.
    • Bone-to-implant contact initiated apically and progressed coronally, with soft tissue eventually mineralizing to enhance contact.

    Conclusions:

    • Healing of wide marginal defects around implants is characterized by appositional bone growth from the defect's lateral and apical walls.
    • This regenerative process supports osseointegration in challenging defect scenarios.
    • The findings highlight the potential for bone regeneration in peri-implant defects using guided bone regeneration principles.