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Bactericidal activity of daptomycin against Streptococcus pneumoniae compared with eight other antimicrobials
Glenn A Pankuch1, Michael R Jacobs, Peter C Appelbaum
1Department of Pathology, Hershey Medical Center, PO Box 850, Hershey, PA 17033, USA.
The Journal of Antimicrobial Chemotherapy
|February 4, 2003
Abstract:
A spectrum of pneumococci with varying susceptibilities to beta-lactams, macrolides and quinolones was tested for susceptibility to nine antibiotics, including the novel lipopeptide daptomycin. Daptomycin was active against all strains (MIC range 90% killing at 1 h.