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Ambulatory blood pressure and left ventricular mass in older age

M Wendelin-Saarenhovi1, R E Isoaho, J J Hartiala

  • 1Department of Clinical Physiology, Nuclear Medicine and Positron Emission Tomography, Turku University Central Hospital, Turku, Finland. marwen@utu.fi

Scandinavian Journal of Clinical and Laboratory Investigation
|February 5, 2003
PubMed

Insights

Systolic ambulatory blood pressure (ABP) is linked to left ventricular mass (LVM) in older adults. Systolic ABP is a better indicator of LVM than diastolic ABP in the elderly population.

Area of Science:

  • Cardiology
  • Gerontology
  • Hypertension Research

Background:

  • Left ventricular mass (LVM) is a key indicator of cardiac health.
  • Left ventricular hypertrophy (LVH) is associated with increased cardiovascular risk.
  • Understanding blood pressure's role in LVH is crucial for aging populations.

Purpose of the Study:

  • To analyze the association between ambulatory blood pressure (ABP) and LVM in individuals over 64 years old.
  • To describe ABP levels in older adults with and without LVH.

Main Methods:

  • Echocardiography was used to calculate LVM in 490 Finnish adults (mean age 70.7).
  • Ambulatory blood pressure (ABP) was measured.
  • Linear regression analyzed factors associated with LVM; LVH was defined using Framingham criteria.

Main Results:

  • Systolic ABP showed a significant association with LVM.
  • No correlation was found between diastolic ABP and LVM.
  • The prevalence of LVH was 22%; subjects with LVH had higher systolic ABP (132/75 mmHg) compared to those without (123/75 mmHg).

Conclusions:

  • Systolic ABP is significantly associated with LVM in older individuals.
  • Systolic ABP is a stronger predictor of LVM than diastolic ABP in the aged population.
Abstract

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