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Environmental regulation of mutation rates at specific sites
Ruth C Massey1, Angus Buckling
1Nuffield Dept of Clinical Laboratory Sciences, University of Oxford, Level 4, John Radcliffe Hospital, UK. ruth.massey@ndcls.ox.ac.uk
Trends in Microbiology
|February 5, 2003
Abstract:
Recent studies on bacterial adaptation to stress suggest that bacteria can regulate the generation of mutations at specific sites in response to environmental conditions. Here, we review these findings and discuss the circumstances under which these mechanisms might prove advantageous.