Related Experiment Videos
Evaluation of vinylsulfamides as sulfhydryl selective alkylation reagents in protein modification
Min Li1, Robert S Wu, Jane S C Tsai
1Roche Diagnostics Corporation, 9115 Hague Road, Indianapolis, IN 46250, USA. minli88@att.net
Bioorganic & Medicinal Chemistry Letters
|February 5, 2003
Abstract:
The preparation of several model vinylsulfamides is described. Their excellent selective reactivity towards sulfhydryl group with regards to amino group has been demonstrated by the kinetics study between a model vinylsulfamide and cysteine or lysine at different pHs.