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Novel thieno oxazine analogues as antihyperglycemic and lipid modulating agents
Saibal Kumar Das1, K Anantha Reddy, Chandrasekhar Abbineni
1Discovery Chemistry, Dr. Reddy's Research Foundation, Bollaram Road, Miyapur, Hyderabad 500 050, India. saibalkumardas@drreddys.com
Bioorganic & Medicinal Chemistry Letters
|February 5, 2003
Abstract:
A series of phenyl acetic acid and alpha-hydroxy propionic acid derivatives were synthesized. In vivo studies of the compounds indicated compound 2c as the most potent in one of the series, which has both glucose and lipid lowering properties. The syntheses and biological studies have been discussed.