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Mass Isolation and In Vitro Cultivation of Intramolluscan Stages of the Human Blood Fluke Schistosoma Mansoni
Published on: January 14, 2018
Control of gamete formation (exflagellation) in malaria parasites
Abstract:
The only stages of malaria parasites capable of establishing an infection in a mosquito are the gametocytes that circulate in the blood of the veterbrate host. Within minutes of ingestion by a mosquito the gametocytes transform into mature gametes in the process of "exflagellation." This process is controlled in vitro solely by the change in pH in the blood as it moves from the environment of the circulation to that of the atmosphere, the pH rise being mediated by the fall in carbon dioxide tension as the blood equilibrates with the atmosphere.
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