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Related Experiment Videos

Long nocturnal dialysis.

S Alloatti1, A Molino, M Manes

  • 1Nephrology and Dialysis Unit, Regional Hospital, Viale Ginevra 3, I-11100 Aosta, Italy. nephroaosta@libero.it

Blood Purification
|February 5, 2003
PubMed
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Long nocturnal dialysis (LND) is effective for chronic renal failure patients, improving weight, hemoglobin, phosphate levels, and blood pressure. This dialysis method offers good survival and rehabilitation results.

Area of Science:

  • Nephrology
  • Renal Replacement Therapy
  • Dialysis Technology

Background:

  • Increasing dialysis patient numbers necessitated a third long nocturnal dialysis (LND) session.
  • Previous reports indicated excellent survival and rehabilitation outcomes with LND.

Purpose of the Study:

  • To analyze the results of implementing a third LND session.
  • To assess the role of LND among various dialytic treatment options.

Main Methods:

  • 13 patients with over 6 months of LND experience were studied.
  • Evaluated parameters included Kt/V, protein catabolic rate, body weight, serum albumin, hemoglobin, electrolytes, PTH, body water, blood pressure, and medication use.
  • Metabolic evaluation analyzed sodium, potassium, phosphate, and urea kinetics during LND.

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Main Results:

  • Low mortality rate (1 death per 247 patient-months).
  • Significant improvements observed: increased postdialytic weight and hemoglobin, decreased phosphate levels and systolic blood pressure.
  • Metabolic study indicated potential sodium/potassium pump exhaustion and controlled phosphate rebound.

Conclusions:

  • Long nocturnal dialysis (LND) is a valuable tool for managing chronic renal failure.
  • LND is easy to implement and yields positive outcomes.
  • LND facilitates individualized treatment plans for uremic patients when combined with other dialysis modalities.