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Less common methods to treat acne.

Ana Kaminsky1

  • 1Department of Dermatology, Durand Hospital, School of Medicine, University of Buenos Aires, Argentina. anakaminsky@fibertel.com.ar

Dermatology (Basel, Switzerland)
|February 5, 2003
PubMed
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When effective acne medications are unavailable, this review explores topical and systemic treatments, including phototherapy and combination therapies. It examines alternatives like sulfur, salicylic acid, and newer agents for managing acne vulgaris.

Area of Science:

  • Dermatology
  • Pharmacology

Background:

  • Acne vulgaris is a common skin condition with treatment challenges.
  • Medication unavailability due to economic factors or market shortages necessitates exploring alternative therapies.

Purpose of the Study:

  • To review available topical and systemic medications for acne treatment.
  • To explore physical methodologies and phototherapy for acne management.
  • To report on combination therapy for severe inflammatory acne.

Main Methods:

  • Literature review of topical agents (sulfur, salicylic acid, alpha-hydroxy acids).
  • Review of systemic agents (diaminodiphenylsulfone, clofazimine, ibuprofen).
  • Evaluation of physical therapies and phototherapy (blue light, blue-red light).
  • Analysis of combined isotretinoin and methylprednisone use in severe acne.

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Main Results:

  • Identified various topical and systemic drugs for acne treatment.
  • Highlighted the potential of phototherapy, including blue and blue-red light.
  • Reported successful use of combined isotretinoin and methylprednisone in severe inflammatory acne to prevent pseudo-acne fulminans.

Conclusions:

  • A range of therapeutic options exist for acne when standard medications are unavailable.
  • Phototherapy and combination treatments offer promising avenues for managing acne, especially severe forms.