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Technical Modification of the Terminal Ureter During Total Transperitoneal Laparoscopic Nephroureterectomy for Upper Urinary Tract Urothelial Carcinoma
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Published on: November 22, 2019

Distal ureteral stenosis after early adjuvant intravesical mitomycin C application for superficial bladder cancer

Sven Oehlschläger1, A Loessnitzer, Michael Froehner

  • 1Department of Urology, University Hospital Carl-Gustav Carus, Technical University Dresden, Germany.

Urologia Internationalis
|February 5, 2003
PubMed

Insights

A rare case of ureteral stenosis occurred after bladder tumor resection and mitomycin C treatment. This late-onset stenosis, likely influenced by the chemotherapy, was successfully treated with further resection and stenting.

Area of Science:

  • Urology
  • Oncology
  • Surgical Pathology

Background:

  • Transurethral resection is a common procedure for bladder tumors.
  • Mitomycin C instillation is used for chemoprophylaxis to prevent tumor recurrence.

Observation:

  • A patient developed distal ureteral stenosis after bladder tumor resection and mitomycin C instillation.
  • The stenosis recurred late, presenting with severe benign inflammatory reaction.

Findings:

  • The recurrent ureteral stenosis was successfully managed via transurethral resection of scar tissue and ureteric stenting.
  • The timing and severity suggest mitomycin C may influence ureteral stenosis development.

Implications:

  • This case highlights a potential complication of mitomycin C chemoprophylaxis after bladder tumor resection.
  • Further investigation into the link between intravesical chemotherapy and ureteral stenosis is warranted.
  • Successful management strategies for recurrent ureteral stenosis include surgical intervention and stenting.

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