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Knowledge of antiretroviral regimen dosing and adherence: a longitudinal study
Loren G Miller1, Honghu Liu, Ron D Hays
1Division of Infectious Diseases, Harbor-University of California, Los Angeles (UCLA) Medical Center, Torrance 90502, USA. lgmiller@ucla.edu
Abstract:
In a cohort of 128 human immunodeficiency virus-infected patients, we found that patients' knowledge of antiretroviral dosing was suboptimal at regimen initiation but improved with time. Poor medication knowledge 8 weeks after regimen initiation was associated with lower adherence and with a lower level of literacy in a multivariate model (P=.03). Because knowledge deficits are common after antiretroviral regimen initiation, clinicians should assess patients' understanding of medication dosing soon after regimen initiation or change.