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Published on: June 15, 2018
[Observation on specific IgG4 antibody of schistosomiasis patients before and after treatment]
1Institute of Parasitic Diseases, Chinese Academy of Preventive Medicine, Shanghai 200025.
Objective:
To observe the alteration of specific IgG4 antibody of schistosomiasis patients before and after treatment.
Methods:
ELISA.
Results:
The SEA-IgG4 and AWA-IgG4 positive rates of 27 schistosomiasis cases were 96.3% and 100%, respectively, their average OD values were 1.62 and 0.72. 6 months post treatment 18 cases were followed up, the positive rates were 94.4% and 100%, respectively, their average OD values were 1.06 and 0.56, respectively. 12 months post treatment all cases were followed up, the positive rates of SEA-IgG4 and AWA-IgG4 were 96.3% and 92.6%, respectively, their average OD values were 0.99 and 0.58, respectively.
Conclusion:
No obvious changes were found in the SEA-IgG4 and AWA-IgG4 positive rates of 27 schistosomiasis cases before and after treatment, whereas the antibody level of specific IgG4 was decreased.
