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Updated: Jul 21, 2026
Extraction and Purification of Polyphenols from Freeze-dried Berry Powder for the Treatment of Vascular Smooth Muscle Cells In Vitro
Published on: July 5, 2017
[Structural elucidation of a new tetrahydroxystilbene of Radix Polygoni Multiflori Preparata and study on its
1College of Pharmacy, Second Military Medical University, Shanghai 200433, China.
Aim:
To investigate the cardiovascular active constituents of Radix Polygoni multiflori Preparata.
Methods:
Compounds were isolated from the water soluble extract with column chromatography of Sephadex, ODS and HPLC. The compounds were identified on the basis of spectral analysis (IR, EI-MS, FAB-MS, 1HNMR, 13CNMR, 2D-NMR) and phytochemical properties. Its inhibitory effect on the proliferation of bovine vascular smooth muscle cells were bioassayed in vitro.
Results:
One compound was isolated and identified as: 2,3,5,4'-tetrahydroxystilbene-2-O-(6"-O-alpha-D- glucopyranosyl)-beta-D-glucopyranoside.
Conclusion:
Compound I is a new compound with cardiovascular activity.
