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Antibacterial compounds from the leaves of Acanthopanax senticosus
Sanghyun Lee1, Dong-Sun Shin, Ki-Bong Oh
1Natural Products Research Institute and College of Pharmacy, Seoul National University, Seoul 110-460, Korea.
Archives of Pharmacal Research
|February 6, 2003
Abstract:
Chiisanogenin (1), hyperin (2) and chiisanoside (3) were isolated from the leaves of Acanthopanax senticosus, and were tested for their inhibitory activities against 6 strains of bacteria. Among them, chiisanogenin (1) revealed broad but moderate antibacterial activities against G (+) and G (-) bacteria, the minimum inhibitory concentration (MIC) being in the range of 50-100 microg/ml.