Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Frontal-striatal circuit functions: context, sequence, and consequence.

Jean A Saint-Cyr1

  • 1Department of Surgery (Division of Neurosurgery), University of Toronto, ON, Canada. jean@uhnres.utoronto.ca

Journal of the International Neuropsychological Society : JINS
|February 7, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Associative reinstatement memory measures hippocampal function in Parkinson's Disease.

Neuropsychologia·2016
Same author

Regional anatomy of the pedunculopontine nucleus: relevance for deep brain stimulation.

Movement disorders : official journal of the Movement Disorder Society·2013
Same author

Decreased cerebral cortical serotonin transporter binding in ecstasy users: a positron emission tomography/[(11)C]DASB and structural brain imaging study.

Brain : a journal of neurology·2010
Same author

A multicentre study on suicide outcomes following subthalamic stimulation for Parkinson's disease.

Brain : a journal of neurology·2008
Same author

Increased vesicular monoamine transporter binding during early abstinence in human methamphetamine users: Is VMAT2 a stable dopamine neuron biomarker?

The Journal of neuroscience : the official journal of the Society for Neuroscience·2008
Same author

Elevated serotonin transporter binding in depressed patients with Parkinson's disease: a preliminary PET study with [11C]DASB.

Movement disorders : official journal of the Movement Disorder Society·2008

The basal ganglia

Area of Science:

  • Neuroscience
  • Cognitive Science
  • Neuropsychology

Background:

  • The precise function of the basal ganglia in motor and non-motor tasks remains unclear due to its interconnectedness with cortical circuits.
  • Current understanding often focuses on frontal-striatal circuits, yet specific basal ganglia information processing is not well-defined.

Purpose of the Study:

  • To critically review existing data from basic science and clinical studies to clarify basal ganglia information processing.
  • To propose a temporal continuum framework for understanding basal ganglia functions across different domains.

Main Methods:

  • Critical review of basic science and clinical data.
  • Analysis of basal ganglia processing along a temporal continuum: context, sequential information processing, and feedback/reinforcement.

Related Experiment Videos

  • Examination of basal ganglia roles in attentional control, learning guidance, and associative binding.

    • Main Results:

    • Basal ganglia are involved in attentional control, early learning stages (especially reinforcement-based), and associative binding of reward to cues and responses.
    • A temporal framework helps delineate basal ganglia functions, cutting across traditional neuropsychological constructs like attention and memory.
    • Parkinson's disease offers a limited view of basal ganglia function due to dopamine depletion and confounding pathologies.

    Conclusions:

    • A temporal continuum model offers a new heuristic for basal ganglia research.
    • This framework can bridge neurophysiological, functional imaging, and neuropsychological paradigms.
    • Further research is needed to refine our understanding of basal ganglia's role in complex cognitive and motor functions.