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Updated: Aug 5, 2026

A Dual Tracer PET-MRI Protocol for the Quantitative Measure of Regional Brain Energy Substrates Uptake in the Rat
Published on: December 28, 2013
Specific diagnosis of brain disease with double isotope brain scanning
Abstract:
25 patients with known cerebral disease (either CVA's or primary or secondary tumours) diagnosed by clinical and angiographic criteria were submitted to a double isotope imaging technique using 99mTcO4- and 99mTc-EHDP. The different biological behaviour of these radiopharmaceuticals has provided specific and differential diagnosis between vascular and neoplastic disease of the brain. 99mTc-EHDP is shown to be the tracer of choice for the imaging of CVA's and 99mTcO4- is confirmed as the tracer of choice for the imaging of primary or secondary tumours in the brain.
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