Related Experiment Video
Updated: Aug 15, 2026

Development of Cell-type specific anti-HIV gp120 aptamers for siRNA delivery
Published on: June 23, 2011
Plant-derived terpenoids and analogues as anti-HIV agents
I-Chen Sun1, Yoshiki Kashiwada, Susan L Morris-Natschke
1Natural Products Laboratory, School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599-7360, USA.
Abstract:
The plant-derived terpenoids and analogues are reviewed with respect to their anti-HIV activity, structure-activity relationships, and mechanism of action. The active compounds include diterpenoid lactones, phenolic diterpenes, atisane and kaurane diterpenes, phorbol diterpenes, triterpene glycosides, friedelane triterpenes, taraxerane triterpenes, ursane triterpenes, lanostane triterpene, lupane triterpenes, seco-ring A triterpenes, degraded triterpenes, and cucurbitacin triterpenes. Positive new leads for drug development will be highlighted.
Related Concept Videos
Antiviral Nucleoside Inhibitors
Antifungal Agents
Inhibitors of Virion Maturation and Assembly

