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Updated: Sep 27, 2026

Exploring the Pharmacological Action and Molecular Mechanism of Salidroside in Inhibiting MCF-7 Cell Proliferation and Migration
Published on: June 9, 2023
[Effect of isoflavone on human breast cancer cell line MCF-7 and its probable mechanism]
Qingwei Fang1, Ying Liu, Danfeng Song
1Department of Public Health, Harbin Medical University, Harbin 150001, China.
Abstract:
The effects of isoflavone on human breast cancer cell line MCF-7 growth and apoptosis and its probable mechanisms were studied in vitro. The results showed that isoflavone could significantly inhibit the growth and induce the apoptosis of MCF-7 cells. Western Blotting showed that isoflavone increased iNOS protein expression. These results suggested that isoflavone significantly inhibited the MCF-7 growth and induced cell apoptosis by regulating iNOS gene expression.

