Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Leptin in pregnancy.

E Domali1, I E Messinis

  • 1Department of Obstetrics and Gynecology, Medical School, University of Thessalia, Larissa, Greece.

The Journal of Maternal-Fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
|February 8, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Laparoscopic management of a second trimester ruptured spontaneous heterotopic tubal pregnancy mimicking ovarian tumour, a case report.

Facts, views & vision in ObGyn·2023
Same author

Benign descriptors and ADNEX in two-step strategy to estimate risk of malignancy in ovarian tumors: retrospective validation in IOTA5 multicenter cohort.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2022
Same author

Typical ultrasound features of various endometrial pathologies described using International Endometrial Tumor Analysis (IETA) terminology in women with abnormal uterine bleeding.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2020
Same author

Severe maternal morbidity associated with in vitro fertilisation.

BJOG : an international journal of obstetrics and gynaecology·2019
Same author

Blood ghrelin, adiponectin and resistin levels during controlled ovarian stimulation in IVF cycles.

Physiological research·2016
Same author

Chorionic villi derived mesenchymal like stem cells and expression of embryonic stem cells markers during long-term culturing.

Cell and tissue banking·2016

Leptin, a protein crucial for reproductive functions, plays a role in pregnancy. Maternal leptin levels rise during pregnancy, and abnormal levels are linked to complications like diabetes and pre-eclampsia.

Area of Science:

  • Reproductive biology
  • Endocrinology
  • Maternal-fetal medicine

Background:

  • Leptin is a 16-kDa protein encoded by the LEP gene in humans.
  • It is implicated in ovarian function, oocyte maturation, embryo development, and implantation.
  • Leptin is produced by the placenta during pregnancy, with levels increasing in maternal blood, especially in the second trimester.

Purpose of the Study:

  • To explore the physiological role of leptin in pregnancy and fetal development.
  • To investigate the correlation between leptin levels and pregnancy complications.
  • To understand the significance of leptin in maternal and fetal physiology.

Main Methods:

  • Review of existing literature on leptin's role in reproduction and pregnancy.
  • Analysis of maternal and cord blood leptin levels in various pregnancy conditions.

Related Experiment Videos

  • Correlation studies between leptin concentrations and outcomes such as birth weight.

    • Main Results:

    • Maternal leptin levels increase during pregnancy, peaking in the second trimester and declining postpartum.
    • Elevated leptin levels are observed in pregnancies complicated by diabetes mellitus and pre-eclampsia.
    • Cord blood leptin levels show a significant correlation with birth weight.

    Conclusions:

    • Leptin is a significant factor in pregnancy, influencing maternal physiology and fetal growth.
    • Further research is needed to fully elucidate leptin's physiological importance in pregnant women and fetuses.
    • Leptin levels serve as potential biomarkers for pregnancy complications and fetal development.