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Published on: June 10, 2025
Depression in patients with heart failure: physiologic effects, incidence, and relation to mortality
Sue Ann Thomas1, Erika Friedmann, Meenakshi Khatta
1School of Nursing, University of Maryland, Baltomore 21201, USA. Thomas@son.umaryland.edu
Insights
Depression significantly impacts heart failure patients, increasing mortality. Early detection and nursing interventions for depression can improve outcomes and reduce deaths in heart failure management.
Area of Science:
- Cardiology
- Psychiatry
- Nursing
Background:
- Heart failure affects millions, with depression a significant concern.
- Depression in heart failure patients is linked to increased morbidity and mortality.
- Existing research on depression in heart failure is limited.
Purpose of the Study:
- To investigate the effects of depression in heart failure patients.
- To highlight the role of nurses in managing depression in heart failure.
Main Methods:
- Literature review on depression incidence and outcomes in heart failure.
- Analysis of factors influencing depression in heart failure patients.
- Exploration of nursing interventions for depression management.
Main Results:
- Depression incidence in heart failure ranges widely (13%–77.5%).
- Men with heart failure have a higher risk of depression.
- Hospitalized heart failure patients show higher depression rates than outpatients.
- Depression is associated with increased mortality, potentially due to physiological changes.
Conclusions:
- Depression is a critical issue in heart failure management.
- Nurses play a vital role in detecting and treating depression in heart failure patients.
- Reducing depression may decrease mortality rates in heart failure.
Abstract:
Heart failure affects 4.8 million people in the United States. Patients depressed after myocardial infarction have increased morbidity and mortality. Only a few studies have investigated the effects of depression in patients with heart failure. The incidence of depression in heart failure ranges from 13% to 77.5%. Men with heart failure are more likely to become depressed than the general population. Depression incidence is higher in hospitalized patients with heart failure than in stabilized outpatients. In patients with heart failure, depression is associated with mortality. Physiologic changes, which occur in depressed patients, have been implicated as possibly contributing to the increased mortality. Nurses have a major role in the management of patients with heart failure and can be pivotal in the detection and treatment of depression in these patients. Reduction in depression is likely to decrease morality in patients with heart failure.
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