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Platelet Adhesion and Aggregation Under Flow using Microfluidic Flow Cells
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Platelet Adhesion and Aggregation Under Flow using Microfluidic Flow Cells

Published on: October 27, 2009

[The effects of starfish sterol on platelet aggregation]

D Xu1, S Xu

  • 1Section of Drugs and Pharmacology, Department of Pharmacy, Zhongshan University, Guangzhou, 510275.

Zhong Yao Cai = Zhongyaocai = Journal of Chinese Medicinal Materials
|February 11, 2003
PubMed

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The platelet phase, the second stage of hemostasis, commences around 15-20 seconds after an injury. It follows and overlaps with the vascular phase, during which blood vessels constrict to minimize blood loss.
As the injured blood vessel contracts, endothelial cells undergo contraction, revealing collagen fibers in the basement membrane and underlying connective tissue. Furthermore, the plasma membrane of endothelial cells becomes adhesive, preparing the site for platelet adhesion. Platelets...