[Preliminary screen of anti-endotoxin activity of Chinese materia medica]
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1Tongjji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030.
Objective:
To screen Chinese materia medica against E. coli. O111B4 endotoxin.
Method:
70% alcohol extracts from 134 kinds of heat-clearing Chinese materia medica were demonstrated by using limulus test in vitro. The extracts which had anti-endotoxin effects were diluted to demonstrate their minimal anti-endotoxin concertnations.
Results:
75 kinds of Chinese materia medica possessed anti-endotoxin activity in various degrees in vitro.
Conclusion:
Most of heat-clearing Chinese materia medica possess anti-endotoxin effects in vitro.