Related Experiment Video
Updated: Aug 18, 2026
Modeling Brain Metastases Through Intracranial Injection and Magnetic Resonance Imaging
Published on: June 7, 2020
[Pathological analysis of metastatic brain tumors misdiagnosed with MRI]
Chang-li Zheng1, Chun-yan Fu, Kang-xin Hu
1Department of Pathology, Xiangya School of Medicine, Central South University, Changsha 410078, China.
Objective:
To study the pathological basis of metastatic brain tumors misdiagnosed with (MRI).
Methods:
Seven cases were analyzed histopathologically and immunohistochemically, compared with the MRI image.
Results:
All the tumors were single large noduls. Hemorrhage and necrosis of the tumors were seen in all the cases. Cystformation of the tumor, glial cell proliferation and vascular proliferation of peritumoral brain tissues were seen in most cases.
Conclusion:
The secondary changes of metastatic brain tumors and the reactive changes of peritumoral brain tissues are the major causes of MRI misdiagnosis.
