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A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
Published on: June 4, 2017
[Skin tests for trophallergens and asthma].
1Centre Hospitalier Intercommunal, 40 avenue de Verdun, 94000 Créteil.
Allergie Et Immunologie
|February 11, 2003
Summary
Investigating food allergies in asthmatic children requires careful clinical history. Positive food allergen tests alone rarely confirm true food allergy without associated symptoms and further testing.
Area of Science:
- Pediatric Allergy and Immunology
- Respiratory Medicine
Context:
- Asthma in children is a complex condition with multifactorial causes.
- The role of food allergens in pediatric asthma remains a subject of debate.
- Accurate diagnosis of food allergy is crucial for effective management.
Purpose:
- To clarify the diagnostic significance of trophallergic (food allergen) testing in asthmatic children.
- To determine the reliability of positive food allergen tests in the absence of specific clinical indicators.
- To evaluate the predictive value of food allergen sensitization for future asthma development in infants.
Summary:
- Asthma is seldom solely caused by food allergy; associated clinical signs are key indicators.
- Positive food allergen tests in asthmatic children often do not signify true food allergy without corroborating symptoms.
- A double-blind oral food challenge is the gold standard for confirming food allergy.
- In infants, positive skin tests for food allergens indicate atopy but are poor predictors of asthma without clinical allergy.
Impact:
- Highlights the importance of clinical evaluation over solely relying on allergen testing for diagnosing food allergy in asthmatic children.
- Emphasizes the need for rigorous diagnostic protocols, including provocation tests, to confirm food allergies.
- Provides guidance on interpreting allergen sensitization in infants, differentiating atopy from predictive markers for asthma.
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