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Related Experiment Videos

Can breast-feeding protect against schizophrenia? Case-control Study.

M Amore1, C Balista, R G McCreadie

  • 1Institute of Psychiatry, University of Parma, Italy.

Biology of the Neonate
|February 11, 2003
PubMed
Summary

Breast-feeding is not less common in adults who develop schizophrenia. However, longer breast-feeding duration may postpone the onset of schizophrenia symptoms.

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Area of Science:

  • Neuroscience
  • Psychiatry
  • Pediatrics

Background:

  • Human milk contains essential long-chain polyunsaturated fatty acids (LCPUFAs) crucial for central nervous system development.
  • Schizophrenia is increasingly understood as a neurodevelopmental disorder.
  • This study investigates a potential link between early nutrition and schizophrenia development.

Purpose of the Study:

  • To compare breast-feeding incidence and duration in schizophrenia patients, their siblings, and controls.
  • To explore the relationship between breast-feeding duration and age of schizophrenia onset.

Main Methods:

  • A case-control study involving 113 schizophrenia patients, 140 siblings, and 113 controls.
  • Breast-feeding histories were collected via maternal interviews.

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Main Results:

  • No significant difference in breast-feeding incidence was observed across the groups.
  • A positive correlation was found between breast-feeding duration and age at schizophrenia onset (r = +0.25, p < 0.02).

Conclusions:

  • Breast-feeding is as common in individuals who develop schizophrenia as in controls.
  • Extended breast-feeding may be associated with a delayed onset of schizophrenia.