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Related Experiment Videos

Bladder outlet resistance.

Ries Kranse1, Ron van Mastrigt

  • 1Department of Urology/Urodynamics, Erasmus University Rotterdam, The Netherlands.

The Journal of Urology
|February 11, 2003
PubMed
Summary

We developed a method to objectively compare bladder outlet resistance quantification. The average pressure at the bottom of the pressure flow plot best predicts post-void residual, offering a single, effective index.

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Area of Science:

  • Urology
  • Medical Engineering

Background:

  • Quantifying bladder outlet resistance is crucial for diagnosing lower urinary tract symptoms.
  • Existing methods for assessing bladder outlet resistance lack objective comparison standards.

Purpose of the Study:

  • To develop and validate an objective method for comparing different models of bladder outlet resistance quantification.
  • To identify the most effective index for predicting post-void residual volume.

Main Methods:

  • Analysis of voiding cystometries from 131 male patients.
  • Fitting various bladder outlet resistance models to the pressure-flow plot data.
  • Using model parameters and bladder contractility as predictors for post-void residual.

Main Results:

  • Bladder outlet pressure decrease is linearly related to flow rate.
  • Both flow-dependent and flow-independent components of pressure significantly predict residual volume.
  • A single index, the average pressure at the bottom of the pressure-flow plot, effectively predicts residual volume.

Conclusions:

  • An objective comparison method for bladder outlet resistance models was established based on predicting post-void residual.
  • The average pressure of the bottom of the pressure-flow plot is a superior index for bladder outlet resistance quantification.
  • This index efficiently combines flow-dependent and independent factors without compromising predictive power.

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