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[Suicide attempt with high-dose ecstasy].

J Hinkelbein1, A Gabel, M Volz

  • 1Institut für Anästhesiologie und Operative Intensivmedizin, Universitätsklinikum Mannheim. hinkelbein@akutmedizin.de

Der Anaesthesist
|February 11, 2003
PubMed
Summary
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This case report details a 16-year-old female

Area of Science:

  • Toxicology
  • Emergency Medicine
  • Cardiology

Background:

  • Ecstasy (3,4-methylenedioxymethamphetamine) is a recreational drug with significant cardiovascular and neurological risks.
  • Adolescent polydrug use and suicide attempts present complex clinical challenges.
  • Understanding the acute effects of high-dose Ecstasy ingestion is crucial for emergency care.

Observation:

  • A 16-year-old female presented with severe symptoms after ingesting 30 Ecstasy tablets.
  • Initial presentation included tachycardia, hyperdynamic circulation, dehydration, and myoclonus.
  • Despite general anesthesia, intubation, gastric lavage, and antihypertensive therapy, hypertension persisted.

Findings:

  • Acute Ecstasy intoxication can cause a sympathomimetic crisis with persistent hypertension.

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  • Management requires airway control, hemodynamic stabilization, and drug elimination.
  • Neurological status normalized post-extubation, indicating potential reversibility of acute effects.

    • Implications:

    • Emergency physicians must be vigilant for increasing cases of Ecstasy intoxication.
    • Prompt symptomatic treatment is essential due to the lack of a specific antidote.
    • This case highlights the severe, potentially life-threatening, cardiovascular and neurological sequelae of high-dose Ecstasy use in adolescents.